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Endocrine Abstracts

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ea0025oc3.1 | Pituitary and thyroid | SFEBES2011

Development of a novel mass spectroscopy-based method for determining serum IGF1: assessment in a cohort of newly diagnosed subjects with acromegaly

Halsall David , Kay Richard , Taylor Kevin , Annamalai Anand , Kandasamy Narayanan , Wark Gwen , Pleasance Steve , Gurnell Mark

Background: The recently published ‘Consensus on Criteria for Cure of Acromegaly’ (Giustina et al. JCEM, 2010) highlighted concerns regarding the quality of currently available insulin-like growth factor 1 (IGF1) immunoassays which may contribute, at least in part, to the discordance between GH and IGF1 that is observed in up to 30% of patients with acromegaly after treatment. The development of mass spectroscopy (MS)-based technology has been proposed ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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